As newer modalities become more complex, understanding how to maintain protein stability and develop robust formulations becomes of paramount importance. This conference aims to shed light on the latest advancements, challenges and strategies in this field, such as the emergence of in-silico simulations, predictive models for stability, and machine learning to optimize formulations to ensure safety, efficacy and commercial viability. At the same time, emerging biophysical methods such as SAXS are gaining entry into the industry and pave the way for innovative solutions that will shape the future of biotechnology.